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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA1
All Species:
23.64
Human Site:
Y1237
Identified Species:
47.27
UniProt:
O95477
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95477
NP_005493.2
2261
254286
Y1237
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
Chimpanzee
Pan troglodytes
XP_001138040
2261
254230
Y1237
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
Rhesus Macaque
Macaca mulatta
XP_001106713
1081
120445
K175
G
L
S
K
K
H
V
K
A
E
M
E
Q
M
A
Dog
Lupus familis
XP_538773
2261
253895
Y1237
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P41233
2261
253955
Y1237
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
Rat
Rattus norvegicus
Q7TNJ2
2170
237702
G1203
E
A
S
V
L
E
N
G
E
L
A
K
L
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516009
2266
254238
Y1241
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
Chicken
Gallus gallus
NP_989476
2260
254054
Y1237
S
D
L
G
I
S
S
Y
G
I
S
E
T
T
L
Frog
Xenopus laevis
NP_001089022
2363
267334
F1330
G
D
L
G
L
S
S
F
G
I
S
D
T
P
L
Zebra Danio
Brachydanio rerio
XP_683123
2330
265308
S1312
T
L
G
D
M
G
L
S
S
F
G
I
S
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
V799
T
D
V
C
T
H
Y
V
K
E
A
E
R
G
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
D977
R
A
R
S
A
C
R
D
R
K
T
V
A
F
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
47
94.9
N.A.
95
50.8
N.A.
89.1
85.4
49.8
51.1
N.A.
N.A.
N.A.
24.9
N.A.
Protein Similarity:
100
99.7
47.5
97.6
N.A.
97.3
67.4
N.A.
94.6
92.6
66.8
67.8
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
100
100
66.6
0
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
40
N.A.
100
100
86.6
20
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
0
0
9
0
17
0
9
0
9
% A
% Cys:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
9
0
0
0
9
0
0
0
9
0
9
0
% D
% Glu:
9
0
0
0
0
9
0
0
9
17
0
67
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
9
0
9
0
0
0
9
0
% F
% Gly:
17
0
9
59
0
9
0
9
59
0
9
0
0
9
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
0
0
0
59
0
9
0
0
0
% I
% Lys:
0
0
0
9
9
0
0
9
9
9
0
9
0
0
0
% K
% Leu:
0
17
59
0
17
0
9
0
0
9
0
0
9
0
67
% L
% Met:
0
0
0
0
9
0
0
0
0
0
9
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
9
0
9
0
0
0
9
0
9
0
0
0
9
0
0
% R
% Ser:
50
0
17
9
0
59
59
9
9
0
59
0
9
0
0
% S
% Thr:
17
0
0
0
9
0
0
0
0
0
9
0
59
50
9
% T
% Val:
0
0
9
9
0
0
9
9
0
0
0
9
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _